David N Krag Selected Research

Therapeutics

5/2022	Development of Clinical-Grade Antibodies against Tumor-Specific Mutations to Target Neuroblastoma.
1/2018	Characterization of sentinel node-derived antibodies from breast cancer patients.
11/2015	Autologous antibodies that bind neuroblastoma cells.
10/2010	Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial.
2/2010	Novel beta-lactamase-random peptide fusion libraries for phage display selection of cancer cell-targeting agents suitable for enzyme prodrug therapy.
11/2009	Developing bifunctional beta-lactamase molecules with built-in target-recognizing module for prodrug therapy: identification of Enterobacter Cloacae P99 cephalosporinase loops suitable for randomization and phage-display selection.
11/2009	Identification of single chain antibodies to breast cancer stem cells using phage display.
1/2009	Biopanning Phage-Display Libraries on Small Tissue Sections Captured by Laser Capture Microdissection.
9/2007	Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation.
5/2007	Towards a ligand targeted enzyme prodrug therapy: single round panning of a beta-lactamase scaffold library on human cancer cells.

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David N Krag Research Topics

Disease

35	Neoplasms (Cancer) 05/2022 - 04/2002
17	Breast Neoplasms (Breast Cancer) 05/2018 - 01/2003
4	Melanoma (Melanoma, Malignant) 01/2020 - 08/2006
3	Neoplasm Metastasis (Metastasis) 02/2011 - 04/2006
2	Neuroblastoma 05/2022 - 11/2015
2	Hypersensitivity (Allergy) 10/2010 - 10/2007
1	Infertility (Sterility) 12/2021
1	Pancreatic Neoplasms (Pancreatic Cancer) 04/2006
1	Neoplasm Micrometastasis 11/2003
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2003
1	Activated Protein C Resistance (APC Resistance) 01/2003

Drug/Important Bio-Agent (IBA)

13	LigandsIBA 08/2013 - 10/2002
12	Peptides (Polypeptides)IBA 05/2022 - 04/2002
11	AntibodiesIBA 05/2022 - 09/2005
6	Proteins (Proteins, Gene)FDA Link 05/2022 - 04/2006
6	Indicators and Reagents (Reagents)IBA 01/2018 - 02/2010
4	beta-Lactamases (beta-Lactamase)IBA 06/2010 - 05/2007
4	Keratins (Keratin)IBA 11/2009 - 11/2003
3	Immunoglobulin G (IgG)IBA 05/2018 - 01/2017
3	VaccinesIBA 01/2018 - 01/2017
3	Single-Chain AntibodiesIBA 01/2015 - 11/2009
3	Cyclic PeptidesIBA 01/2012 - 09/2007
3	Focal Adhesion Protein-Tyrosine KinasesIBA 01/2012 - 09/2007
3	ParaffinIBA 02/2011 - 11/2009
3	EnzymesIBA 02/2010 - 05/2007
3	ProdrugsIBA 02/2010 - 05/2007
2	GRB7 Adaptor ProteinIBA 01/2012 - 04/2006
2	Coloring Agents (Dyes)IBA 10/2010 - 10/2007
2	Cysteine (L-Cysteine)FDA Link 06/2010 - 02/2010
2	DNA (Deoxyribonucleic Acid)IBA 02/2010 - 05/2007
1	EndotoxinsIBA 12/2021
1	AntigensIBA 01/2020
1	Neoplasm Antigens (Tumor Antigens)IBA 01/2020
1	Combined Antibody TherapeuticsIBA 01/2020
1	AutoantibodiesIBA 01/2018
1	Immunoglobulin A (IgA)IBA 01/2018
1	Immunoglobulin M (IgM)IBA 01/2018
1	Cancer VaccinesIBA 01/2017
1	Immunoglobulin Light Chains (Immunoglobulin Light Chain)IBA 01/2015
1	A 17 (A-17)IBA 04/2014
1	G7-18NATEIBA 01/2012
1	ErbB-2 ReceptorIBA 09/2011
1	Antineoplastic Agents (Antineoplastics)IBA 11/2007
1	Amino Acids FDA Link 04/2005
1	DisulfidesIBA 04/2005
1	AntithrombinsIBA 01/2003
1	Protein CIBA 01/2003
1	Protein SIBA 01/2003
1	Tamoxifen FDA LinkGeneric 01/2003
1	Cytotoxins (Cytolysins)IBA 10/2002
1	Peptide LibraryIBA 10/2002

Therapy/Procedure

15	Therapeutics 05/2022 - 04/2002
3	Lymph Node Excision (Lymph Node Dissection) 10/2010 - 10/2007
1	Immunotherapy 05/2018
1	Injections 04/2014
1	Intravenous Infusions 08/2013
1	Segmental Mastectomy (Lumpectomy) 09/2010
1	Drug Therapy (Chemotherapy) 08/2010
1	Lasers (Laser) 08/2009